A new assay rapidly detected pancreatic ductal adenocarcinoma and differentiated it from noncancer pancreatic diseases by ...

In a recent study, PAC-MANN identified pancreatic ductal adenocarcinoma samples with 98% specificity and 73% sensitivity across all stages.

Sarepta Therapeutics, Inc. (NASDAQ:SRPT), the leader in precision genetic medicine for rare diseases, today reported ...

Similar to primary HSCs, both lines express key receptors regulating hepatic fibrosis, including platelet derived growth factor receptor β (βPDGF-R), obese receptor long form (Ob-R L), and discoidin ...

A disintegrin and metalloproteinase 17 (ADAM-17) has multiple pathophysiological functions in Alzheimer's disease (AD). However, the clinical relevance of ADAM-17 in AD is not clear yet.This study ...

Methods Bovine cartilage resorption assays, chondrocyte cell-line SW1353 and primary human articular chondrocytes were used with the general proteasome inhibitor MG132 or vehicle to identify a role of ...

为解决胰腺癌治疗难题，浙江大学医学院附属第一医院的研究人员开展了 MMP - 28 与胰腺癌关系的研究。结果发现 MMP - 28 可预测 EGFR 抑制剂疗效。这为胰腺癌治疗提供新思路，强烈推荐科研读者阅读。

Correspondence to: Dr P T G Elkington Department of Infectious Diseases, Imperial College, Hammersmith Hospital, Du Cane Road, London W12 0NN, UK; p.elkington{at}imperial.ac.uk Matrix ...

Objectives Tendinopathy is a frequent clinical problem and represents an extraordinary health economic and socioeconomic ...

Our data further show that claudin-1 regulates Notch-signalling through the regulation of matrix metalloproteinase-9 (MMP-9) and p-ERK signalling to regulate proliferation and differentiation.