Necroptosis is the predominant form of neuronal death after ischemic stroke. This study identifies the deubiquitinating enzyme OTUB2 as a novel regulator of the RIPK1-RIPK3-MLKL necroptotic signaling ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. The SCF (SKP1/CUL1/F-box protein) ubiquitin ...

Six Sigma is a quality management methodology used to help businesses improve current processes, products, or services by discovering and eliminating defects. The goal is to streamline quality ...

The Sigma Healthcare Ltd (ASX: SIG) share price is falling after the company released the results of last night's shareholder vote on the proposed merger with Chemist Warehouse. The Sigma share ...

Sigma investors would be holding their breath right now. That's because Sigma Healthcare shares are not active on the ASX today. The healthcare stock closed at $3.03 a share yesterday after ...

SYDNEY (Reuters) -Australia's Sigma Healthcare shareholders approved in a vote on Wednesday a merger with Chemist Warehouse to create an A$8.8 billion ($5.50 billion) pharmacy and retailing giant.

Inhibitors used in this project were: nocodazole (Calbiochem/Millipore 487928); monastrol (Calbiochem/Millipore 475879); S-Trityl-L-cysteine (STLC; Tocris 2191); MG132 (Calbiochem/Millipore 474790); ...

Other reagents include mouse anti-Flag M2 magnetic beads (Sigma, M8823), SAG (Cayman, #11914), MG132 (Alfa Aesar, J63250), and chloroquine (Acros Organics, #45524). Each digested sample (1 µg aliquot) ...

The development of haematopoietic stem cells into mature erythrocytes – erythropoiesis – is a controlled process characterized by cellular reorganization and drastic reshaping of the proteome ...

All year-end and CSV data is "as traded on the day" and ignores corporate actions (e.g. share splits) ...