The different microtubule dynamics are explained by differing levels of spastin ... In our study, we relied on the alignment of nuclei to delineate the lesion site as in our accumulated experience, ...

In their important manuscript, Costa et al. establish an in vitro model for dorsal root ganglion (DRG) axonal asymmetry, revealing that central and peripheral axon branches have distinct patterns of ...

Here, the authors characterize the structural organization and condensate behavior of the microtubule plus-end tracking protein Bik1, employing SAXS, computational modeling, microscopy ...

Using in vitro reconstitution experiments with purified components, the authors show that five interacting ciliary tip proteins collectively form cork-like structures at microtubule tips and make ...

The coordination between actin and microtubule network is crucial, yet this remains a challenging problem to dissect and our understanding of the underlying mechanisms remains limited. In this study, ...

The katanin family of microtubule-severing enzymes is critical for cytoskeletal rearrangements that affect key cellular processes like division, migration, signaling, and homeostasis. In humans, ...