A photothermal, nanoparticle-based deep brain stimulation system restored motor skills in mice with Parkinson’s-like disease ...

The neuropathological hallmarks of PD include loss of dopaminergic neurons in the midbrain substantia nigra pars compacta (SNpc) and accumulation of Lewy bodies (LBs) containing α-synuclein.

The preliminary data presented in this manuscript seem valuable. The data are currently incomplete and there are numerous technical concerns, some of which may arise from insufficient description of ...

There are three dopaminergic pathways, namely the striatonigral pathway (substantia nigra to caudate and putamen), the mesolimbic pathway (ventral tegmental area of midbrain to limbic areas of ...

The inferior colliculus (IC) and the locus coeruleus (LC) are two midbrain nuclei that integrate multimodal information and play a ... This is consistent with the existence of an important ...

Parkinson's disease (PD), a common neurodegenerative disorder, is characterised by a selective loss of dopaminergic (DA) neurons from the pars compacta of the substantia nigra, and the formation of ...

Striatal dopamine (DA) release regulates reward-related learning and behavioural activation and is believed to consist of a short-lived phasic and continuous tonic component. Here, we build a ...

A Colorado Springs family hopes to win what they believe would be a landmark legal verdict by proving to jurors next month that mold exposure in a rented apartment caused Parkinson's disease in a ...

Feb. 19, 2025 — Researchers find large language models process diverse types of data, like different languages, audio inputs, images, etc., similarly to how humans ...

Our ultimate goal is to create precise brain therapies that can restore normal brain function in people with Parkinson’s ...