Creatine kinase M2 (CKMT2) plays a key role in mitochondrial dysfunction in type 2 diabetes, affecting energy metabolism in skeletal muscle. A new study from Karolinska Institutet, published in ...

Autophagy contributes to intracellular quality control by degrading defective proteins and organelles, such as polyubiquitinated proteins and damaged mitochondria. Alternatively, autophagy is induced ...

Glycosphingolipids (GSLs) are vital constituents of cells, and changes in their content and composition are important factors causing mitochondrial dysfunction in diabetic cardiomyopathy; however, the ...

In summary, the dysregulation of mitochondria, lysosomes, and the trans-Golgi network underlies the activation of the NLRP3 inflammasome in POCD, highlighting the intricate relationship between ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Inflammatory bowel disease (IBD) is a disorder ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Mechanical control is fundamental for cellular ...