Here, we investigate age-related impairments in calvarial bone healing and introduce a novel two- part rejuvenation strategy to restore youthful repair. We demonstrate that aging negatively impacts ...

In conclusion, by identifying PEBP1 as an amplifier of mitochondrial stress signals, our study provides new insights into cytoplasmic mechanisms which ensure appropriate responses to acute ...

Oleuropein enhances mitochondrial calcium uptake, reversing age-related declines in muscle function and energy metabolism, ...

New research reveals the pivotal role of a mitochondrion-localized protein, PtoRFL30, in the wood formation of poplar trees.

VPS13A disease (also known as Chorea-Acanthocytosis, ChAc) is a representative subtype of the neuroacanthocytosis (NA) syndromes, characterized by neurodegeneration in the central nervous system and ...

Additionally, alcohol disrupts lipid and carbohydrate metabolism, impairing fatty acid oxidation, gluconeogenesis, and mitochondrial homeostasis, which results in liver fat accumulation and ...