Major companies in the dry powder inhaler market are focusing on innovation, developing products with muscarinic antagonists for the treatment of chronic obstructive pulmonary disease (COPD), and ...
Muscarinic (M) receptors involved in the airway tone regulation are as follows: M1 receptors, present on the cholinergic ganglia, with the role of facilitating neural transmission; M2 receptors ...
Emraclidine is a selective muscarinic M4 receptor-positive allosteric modulator (PAM) that is designed to have a limited effect on dopamine neurotransmission, a mechanism thought to contribute to ...
Ensifentrine improved symptoms, lung function, and quality of life according to pooled data from the phase 3 ENHANCE trials, and should now be considered as a follow-up add-on treatment for patients ...