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News Medical on MSNNeurofilament light as a translational biomarker from preclinical drug discovery to clinical applicationNeurofilament light (NFL) is a powerful and sensitive biomarker for tracking neuronal health and disease progression.
visualizes axons in an area-specific maturation patternin human fetal brain; visualizes aberrantly sprouting axons in neuriticplaques derived from cortico-cortical fibers in A.D. and identifies loss ...
The Multiple Sclerosis Functional Composite (MSFC) reached a worsening inflection point with menopause (slope difference, 0.08) and an increase in serum neurofilament light chain (slope difference, −0 ...
phosphorylated neurofilament H and, to a lesser extent, neurofilament M is detected in most mammalian species, in thick and thin axons but not cell bodies ...
INM-901 significantly reduced pro-inflammatory cytokines associated with Alzheimer's Statistically significant reduction in neurodegeneration marker, neurofilament light chain ('NfL') mRNA profile ...
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