G4表示聚酰胺-胺（PAMAM）树枝状聚合物的第四代。 G4-PAMAM具有适中的分子量和复杂的结构，适用于多种生物医学应用。 Tf和tamoxifen修饰： Tf通常指转 ...

应用：该共聚物可用于基因递送、药物递送等领域，实现分子的精准传递和缓释。 h-PAMAM-g-PEG： 定义：h-PAMAM-g-PEG指的是超支化聚酰胺胺（h-PAMAM）接枝聚乙二醇（PEG）形成的复合物。 特性：超支化聚酰胺胺具有三维树枝状结构，提供了丰富的表面官能团和内部 ...

Dextran-PAMAM是通过将聚酰胺胺（PAMAM）树枝状大分子接枝到葡聚糖上而形成的一种复合材料。 葡聚糖是一种天然多糖，具有良好的生物相容性和可降解 ...

Nanomedicine. 2012;7(8):1225-1233. Most of the strategies described for the passage of drugs across the BBB can be enhanced by nanotechnology and some of the mechanisms involved include: NPs open ...

Herein, we attempt to employ a functionalized nanoparticle drug carrier system based on polyamine-amine (PAMAM) dendrimers for targeted delivery of resveratrol in hepatocellular carcinoma cancer ...

PAMAM dendrimers can hold DNA in cavities and act as nonimmunogenic vectors for in vivo gene transfer. The combination of a gene and NP with a surfactant coating can facilitate gene transfer in ...

Over the past 30 years, DNA delivery, especially via the nonviral route (i.e., transfection), has become a powerful and popular research tool for elucidating gene structure, regulation, and function.