Oxidative stress occurs when there's an imbalance between the production of ROS and the body's ability to counteract their ...

Findings on isoniazid-resistant M. tuberculosis reveal key vulnerabilities, suggesting new avenues for treatment strategies ...

NOVEMBER 19, 2024 — UTSA faculty are leveraging their expertise to fight Mycobacterium tuberculosis (Mtb), the germ ...

This study presents important findings on cold tolerance shared between hibernating and non-hibernating mammals, identifying a key molecule, GPX4, through multi-species genome-wide CRISPR screens. The ...

Selenium, a vital trace element, is crucial for various bodily functions, especially for its role as an antioxidant and in ...

Whole genome CRISPRi screening identifies druggable vulnerabilities in an isoniazid resistant strain of Mycobacterium ...

A recent study from the University of Würzburg unveiled a key enzyme involved in producing selenoproteins, opening new ...

A recent study from the University of Würzburg unveiled a key enzyme involved in producing selenoproteins, opening new strategies for treating certain types of cancer in children.

The research also highlights potential avenues for repurposing existing drugs. Researchers found that trimethoprim and sulfamethoxazole, antibiotics used to treat other diseases, were also effective ...

The researchers used a systems biology approach, combining genetic studies, RNA sequencing and metabolic modeling. They found that deficiencies in an enzyme called catalase-peroxidase, encoded by a ...

They found that deficiencies in an enzyme called catalase-peroxidase, encoded by a gene called katG, make drug-resistant TB more susceptible to bedaquiline. Mutations in katG are the most common ...