Additionally, functional assay with bone marrow-derived macrophages (BMDMs) shows that ENT significantly enhances tumor cell phagocytosis and antigen presentation, increasing the proliferation of ...

This call prompts the immune system to investigate, leading to enhanced immune cell migration, phagocytosis, antigen processing, MHC loading, maturation, and the cross-priming of T cells. This ...

The function of human airway macrophages can be therapeutically manipulated by targeting cellular metabolism to support immunity in the lung, aiding the design of innovative strategies in respiratory ...

ESO-T01 is the first in vivo BCMA CAR-T candidate to reach the clinical stageEarly clinical data are expected in second half of ...

9Experimental and Translational Pathology Platform, AMMICa, INSERM US23/UAR3655, Gustave Roussy, Villejuif, France. 20Department of Pathology, University Paris-Saclay, Gustave Roussy Cancer Center, ...

Additionally, immunohistochemistry (IHC) staining of CD16A and FGL2 performed to detect specific antigens in the tissues, further enhancing the diagnostic and prognostic value. Once stained, a ...

Neutrophils, monocytes and macrophages arise from common precursors, explaining much of their functional and phenotypical overlap. However, these cells also have complementary functions during the ...

Proof-of-concept study to evaluate the safety, tolerability and efficacy of MOv18 IgE in patients with platinum-resistant ovarian cancer ...

MOv18 IgE is an IgE antibody targeting the folate receptor alpha (FR alpha) antigen which is selectively ... cell-mediated cytotoxicity (ADCC) and phagocytosis (ADCP) and release pro-inflammatory ...

This valuable study proposes a novel rapid-entry mechanism of S. aureus that involves the rapid release of calcium from lysosomes. The strength of the paper lies in a very interesting hypothesis; what ...