The FDA cleared the investigational new drug application for LTZ-301, a first-in-class myeloid engager immunotherapy, with a ...

REDWOOD CITY, CA, USA & SHENZHEN, China I4, 2025 I LTZ Therapeutics, an immunotherapy-focused biotech company, today announced that the U.S.

Anti-CD20 mAbs were originally created to treat B cell proliferative diseases such as non-Hodgkin's lymphoma and chronic ...

Single-dose administration of E6F6 could profoundly suppress the levels of hepatitis B surface antigen (HBsAg) and HBV DNA for several weeks in HBV-transgenic ... Immunological analyses suggested that ...

Antigen processing and presentation is the mechanism by which whole antigens are degraded and loaded onto MHC molecules for display on the cell surface for recognition by T cells. Both macrophages ...

State Key Laboratory of Pharmaceutical Biotechnology, Medical School of Nanjing University, Nanjing 210093, China Department of Andrology, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical ...

Neutrophils, macrophages and dendritic cells are the key cells that perform phagocytosis. Phagocytosis is important because it can achieve three goals: Destroy pathogens by breaking them down into ...

Protein antigens typically elicit IgG1 and IgG3 ... lyse antibody-coated target cells. IgG promotes phagocytosis by initiating opsonization, a process whereby pathogens (e.g., bacteria) are ...

She has tried dozens of COVID-19 antigen tests—including while sick with COVID-19. Flu is (still) surging nationwide. You can test for flu infection at home, using any of the combination Covid ...

Phagocytosis, a critical early event in the microbicidal response of neutrophils, is now appreciated to serve multiple functions in a variety of cell types. Professional phagocytes play a central role ...

In jawed vertebrates, including mammals, phagocytosis also helps to initiate the more specific adaptive immune response through antigen-presentation to T lymphocytes (Litman et al., 2005). In the ...