The research in my lab is generally concerned with the biophysical characterization of lipid mediated protein functions. We are particularly interested in studying phosphoinositide mediated signaling ...
Multinational Phase III study is evaluating leniolisib tablets in children aged 4 to 11 years with APDS, a rare primary immunodeficiency Data consistent with the improvements seen in the previously ...
Central to the function of the MVB pathway for trafficking to lysosomes are the endosomal sorting complex required for transport-0 (ESCRT-0), -I, -II and –III complexes, which are represented in ...
The COMMD proteins are a conserved family of proteins with central roles in intracellular membrane trafficking and transcription. They form oligomeric complexes with each other and act as components ...