By exploring the conservation and functional diversity of RIPK3 and related RHIM-containing proteins across vertebrates, this important work sheds light on the evolutionary dynamics of these key ...

1Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, Maryland. 2Department of Gynecology and Obstetrics, Johns Hopkins University School of Medicine, Baltimore, Maryland.

Together, these results suggested that the S-phase checkpoint response is enhanced when PLK1 fails to phosphorylate RAD9. Cells must overcome environmental stresses that have the potential to disturb ...