CRISPR screening is an application of this technology, and we can do the screens in two ways. Our pooled format takes huge numbers of lentiviral guide RNAs and delivers them to a large population ...

To illustrate the feasibility of targeted sequencing in conjunction with CRISPR screens, a single-cell RNA sequencing experiment was conducted using a WTA approach. Here, all expressed genes are ...

The findings also reveal a potential limitation of pooled CRISPR screens in studying parasite biology in live hosts. The study was lead by authors Francesca Torelli and Diogo M. da Fonseca ...

In their article published in Nature Methods, the researchers applied PERISCOPE to execute three whole-genome CRISPR screens to create ... to analyze optical pooled screening data at scale." ...