Discover how next-generation kinase inhibitors are transforming clinical therapy byovercoming resistance and enhancing ...

Cystic fibrosis is a life-threatening disease predominantly with respiratory symptoms. Most of the subjects with the disease harbor the F508del variant in the CFTR gene that causes the protein to ...

The cyclic AMP/protein kinase A (cAMP/PKA) pathway is one of the most common and versatile signal pathways in eukaryotic cells. A-kinase anchoring proteins (AKAPs) target PKA to specific substrates ...

Greatwall, a conserved MAST-like kinase with crucial mitotic entry functions, is curiously absent in worms. Here, the single ...

In cancers, all translocations involving ALK produce fusion proteins with constitutive tyrosine kinase activity that in most cases derives from spontaneous dimerization induced by the different ...

CUO-Recherche, Centre de recherche du CHU de Québec and Département d’ophtalmologie, Faculté de médecine, and Regroupement stratégique PROTEO, Université Laval, Québec, Québec G1V 0A6, Canada Centro ...

Protein kinase C (PKC) is as a family of serine/threonine kinases that can be activated by Ca 2+, phospholipid and diacylglycerol. PKC plays an important role in oocyte maturation and activation.

Your body produces the enzyme creatine kinase (CK) or creatine phosphokinase to keep your muscles functioning properly. Healthcare providers use the CK test to check levels of this protein in your ...

The recommended dietary allowance (RDA) for protein is set at 0.36 grams (g) of protein per pound of your body weight (0.8 g per kilogram). Remember that this reflects the minimum protein required ...

Herpesvirus infection may contribute to Alzheimer’s disease through transposable element activation and neuroinflammation.

The breast of chicken, sometimes referred to as the white meat, is low in fat. A 3.5-ounce serving of cooked, skinless chicken breast contains 31 grams (g) of protein. Chicken also contains B vitamins ...

Furin is identified as the key enzyme responsible for cleaving the apelin precursor. Inhibiting this cleavage could serve as ...