Proteolysis is the enzymatic process by which proteins are degraded into their component polypeptide or amino acid parts. This generally occurs through protease-mediated hydrolysis of peptide ...
Save the Sound: Members of Arvinas helped preserve the Long Island Sound and Greater New Haven area by collecting over 287 pounds of trash, contributing to efforts to protect local wildlife and ...
BioTheryX’s technology platform centers on targeted protein degradation, including PHM ‘molecular glues’, PROteolysis TArgeting Chimeras (PROTACs/PTCs) and monovalent degraders that enable ...
Signal transduction across membranes through regulated intramembrane proteolysis is conserved throughout all domains of life. In the SREBP pathway of human cells, the membrane-bound SREBP ...