Save the Sound: Members of Arvinas helped preserve the Long Island Sound and Greater New Haven area by collecting over 287 pounds of trash, contributing to efforts to protect local wildlife and ...

【导读】蛋白水解靶向嵌合体（PROteolysis TArgeting Chimeras, PROTACs）被认为是下一个重磅疗法。然而，由于其固有的局限性，PROTACs的疗效经常受到组织穿透能力有限以及其作用部位的细胞内化不足的影响。10月18日 ...

Alongside other emerging technologies, such as PROTACs (PROteolysis Targeting Chimeras) and AI-driven systems, CRISPR promises to usher in a new phase of personalized cancer therapy. In this editorial ...

Biotechnology Co. Ltd. has disclosed proteolysis targeting chimeras (PROTACs) comprising a cereblon (CRBN) ligand coupled to a mitogen-activated protein kinase kinase kinase kinase 1 (MAP4K1; HPK1; ...

Nanjing Mingde New Drug Research Co. Ltd. has designed proteolysis targeting chimera (PROTAC) compounds comprising an E3 ubiquitin ligase binding moiety covalently linked to a GTPase KRAS (G12D mutant ...

First PROTAC Drug Is Expected To Enter The Market By 2027 Says Kuick In New StudyDelhi, Oct. 11, 2024 (GLOBE NEWSWIRE) -- ...

The company is developing molecules that boost the ubiquitin-independent protein degradation activity of 20S proteasomes in ...

Currently There Are More Than 50 PROTAC Drugs In Clinical Trials And Majority Are For Cancer As Per Recent Study By Kuick ...

The Hilo Meishoin Mission monthly newsletter is often full of history and interesting facts about the people and places of Japan. Reverend Junshin Miyazaki is great if you are interested in getting ...

Research over the last two decades has extended the paradigm of ATP- and ubiquitin-dependent proteasomal protein degradation by discovering that intrinsically unstructured proteins (IUPs) can be ...

International Paper Company; Public dealing disclosure ...

The molecule ACBI3 developed by multi-disciplinary teams in the laboratory of Professor Alessio Ciulli and Boehringer Ingelheim is based on a class of small molecules called PRoteolysis TArgeting ...