Cancer cells resist chemotherapy in low-glucose environments by conserving pyrimidine nucleotides, reducing drug ...

Laboratory experiments with cancer cells have revealed two ways in which tumors evade drugs designed to starve and kill them.

The paper introduces DeepTX, a valuable deep-learning framework linking stochastic, mechanistic modelling with single-cell RNA sequencing data to investigate transcriptional burst kinetics on a genome ...

NYU Langone researchers found cancer cells resist chemotherapy in low-glucose environments by conserving pyrimidines and ...

It turns out that just before developing the nasty skin eruption, the man had manually squeezed a dozen limes, then headed to ...

Chemotherapy drugs can kill cancer cells by halting DNA replication, but a glucose-depleted environment can help cancer cells ...

Discover how cancer cells survive in low-glucose environments and evade chemotherapy-induced death. New study sheds light on ...

rheumatology.medfac.leidenuniv.nl Leflunomide is a selective inhibitor of de novo pyrimidine synthesis. In phase II and III clinical trials of active rheumatoid arthritis, leflunomide was shown to ...