8月19日,中国科学院成都生物研究所生物资源利用中心王飞研究团队联合四川大学化学学院冯小明院士和董顺喜教授团队在药物化学国际顶级期刊Journal of Medicinal Chemistry上发表题为“Discovery of a Covalent Inhibitor of Pro-Caspase-1 Zymogen Blocking NLRP3 Inflammasome Activation ...
Halia Therapeutics, Inc. (Halia), a clinical-stage biopharmaceutical company pioneering innovative treatments for inflammatory and neurodegenerative diseases, today announced that it will showcase its ...
Psoriasis is a multifactorial immune-mediated inflammatory disease. Its pathogenesis involves abnormal accumulation of neutrophils and T-cell related abnormalities. Pyroptosis is a type of regulated ...
This valuable study on strategies used by Pseudomonas to subvert hots immunity identifies a new immune evasion strategy. The study presents solid evidence on the cleavage of VgrG2B by Caspase 11 and ...
Pyroptosis results in systemic release of inflammatory cytokines, IL-1β and IL-18, and ASC specks, w Neurological diseases, which affect up to 16 million people over 18 years old in the US ...