The fall in AGIO stock comes after reports of an unexpected side effect linked to its sole-marketed drug Pyrukynd in thalassemia patients.

Sometimes, people with iron deficiency anemia don't respond to treatment with iron supplementation and may go months to years with little to no improvement in anemia. This can happen if the dose is ...

The Phase 3 ENERGIZE and ENERGIZE-T trials enrolled a total of 452 patients reflective of the real-world thalassemia population. The results demonstrated that mitapivat improves hemolytic anemia and ...

Single molecule nanopore analysis is used to reveal adenylate kinase global dynamics in real time. It was found that allosteric interactions guide domain motions and substrate affinity ...

A B12 deficiency in females can cause symptoms such as fatigue, tingling feet, or depression. The symptoms of a B12 deficiency are not necessarily any different between males or females.

Lindy Noel's mom always knew her daughter was going to change the world. She just didn't know it would be the world of NHL ...

So, too, has Porty learned to manage his chronic case of pyruvate kinase deficiency (PKD), not to be confused with polycystic kidney disorder (also PKD, which we'll get to in a minute).

Rocket Pharmaceuticals, Inc. (NASDAQ: RCKT), a fully integrated, late-stage biotechnology company advancing a sustainable ...

Leukocyte Adhesion Deficiency-I (LAD-I), a severe pediatric genetic disorder that causes recurrent and life-threatening infections which are frequently fatal, and Pyruvate Kinase Deficiency (PKD ...

Vitamin D deficiency is a condition in which your body does not get or process enough vitamin D. Signs of vitamin D deficiency include bone pain, fatigue, and weakness. Some people with the ...

A vitamin B12 deficiency can lead to nerve and brain damage and anemia. Early symptoms include weakness, constipation, and depression. It can result from dietary factors, medication use ...

In this important study, the authors found, with the use of statistical methods, that compound heterozygous rare deletion variants affecting the kinase-domain of non-receptor tyrosine kinase TNK2/ACK1 ...