To Jubao Duan of the University of Chicago, the authors provide compelling evidence. That tau dysregulation derails lipid droplets “provides novel mechanistic insight into how accumulation of human ...

What actually happens in the brain in cases of depression? Relatively unknown brain cells—"astrocytes"—are believed to play ...

New research shows astrocytes can remove Alzheimer’s-related amyloid-beta via autophagy, offering a promising new direction ...

RxJava – Reactive Extensions for the JVM – a library for composing asynchronous and event-based programs using observable sequences for the Java VM.

In an ALS study, growth factor FGF4 reduced the activity of star-shaped cells called astrocytes but did not stop motor ...

Here we dissect the heterogeneity in metastasis-associated astrocytes using scRNAseq and report a population that blocks the antitumoral activity of infiltrating T cells. This pro-tumoral activity is ...

(A) Increased expression of autophagy factors (LC3B, observed as blue dots) in astrocytes (GFAP) in the brain tissues of AD patients. (B) Increases in reactive astrocytes and autophagy gene ...

"A strength overused is a weakness." I've shared this quote many times in my coaching conversations with leaders over the years. In a recent conversation with a highly accomplished and high ...

13 were more likely to emerge. Mic.13 helped spark tau pathology, mediating a third of the association between plaques and tangles. Mic.13 and tangles together triggered a reactive astrocyte state, ...