A gene regulatory network is a set of genes, or parts of genes, that interact with each other to control a specific cell function. Gene regulatory networks are important in development ...

Non-opioid pain therapies are entering an unprecedented era, marked by the landmark FDA approval of Vertex’s Journavx and a ...

Collins, along with Matthew Lau ’25, developed the affordable CRISPRKit to make CRISPR gene-editing technology accessible to high school students underrepresented in the sciences. The kit was ...

Gene expression is the generation of a functional gene product from the information encoded by a gene, through the processes of transcription and translation. Gene products are often proteins ...

Copyright 2025 The Associated Press. All Rights Reserved. Chicago Chess Records producer Gene Barge attends a screening of the film “Cadillac Records,” about ...

mumc.nl Over the past years our SFN-cohort has expanded to 1502 patients. Aims of the current study were to provide more precise data on SCN9A, SCN10A and SCN11A variant frequencies and a rationale ...

Navega's epigenetic therapy, NT-Z001, targets the gene SCN9A that encodes for NaV1.7, a sodium channel responsible for pain signal transmission. NT-Z001 is a non-addictive gene therapy for chronic ...

Patients had already undergone expert phenotyping, laboratory investigation and gene sequencing, but were without a genetic diagnosis ... We interrogated our data for Mendelian causes of ...

of Navega Therapeutics will support translational research to develop an AAV epigenetic gene therapy for gain-of-function SCN9A disorders and chronic pain. The proposed gene therapy targets the gene ...

By introducing a gene from single-celled organisms into mouse cells, they generated stem cells capable of contributing to the development of a living mouse. The team led by Dr Alex de Mendoza of the ...

Not all stressors have the same impact on health. Stress arising from threats to social safety is most likely to affect psychological, biological, and clinical outcomes. This is the conclusion ...

Dec. 4, 2024 — Researchers have uncovered a serious side effect of using the CRISPR-Cas gene scissors. A molecule designed to make the process more efficient destroys parts of the ...