Mechanistically, we found that PGAM regulates Treg differentiation by controlling flux through the de novo serine synthesis pathway. The PGAM substrate 3PG is also utilized for serine synthesis, and ...

The recent boost of multi-omics sequence analysis has rapidly progressed the mining of presumed genes encoding enzymes involved in CWPS biosynthesis pathways. In this review, we summarize the ...

Polyunsaturated fatty acids (PUFAs) are important nutrients that play important roles in human health. In eukaryotes, PUFAs can be de novo synthesized through two independent biosynthetic pathways: ...

Biosynthesis is the generation of natural products through enzymatic reactions, as in cellular metabolism. Successive enzymatic reactions by a number of enzymes are generally required to achieve a ...

A cocrystal structure of the enzyme that synthesizes selenocysteine reveals the elegantly simple recognition mechanism for the tRNA molecule for this '21 st amino acid'. The structure resolves ...

Department of Chemistry, University of California, Berkeley, California 94720, United States Department of Molecular and Cell Biology, University of California, Berkeley, California 94720, United ...

The last encampment of the Israelites on the eastern side of the Jordan River was on the Plains of Moab northeast of the Dead Sea near Mount Nebo, a few miles south of today’s Amman, Jordan (Numbers ...

Sharing the pathway safely means leaving a minimum of one meter between yourself and the person that you are passing. When you’re cycling or riding a scooter on a pathway and you approach others from ...

State Key Laboratory of Microbial Technology, Shandong University, Qingdao, Shandong 266237, China Laboratory for Marine Biology and Biotechnology, Qingdao Marine Science and Technology Center, ...

At Trinity, many of our programmes offer pathways to give you the flexibility to focus or expand your areas of interest over your years at Trinity. As a Trinity student, you will have choices to make ...