Many proteins work together to promote spindle microtubule formation during cell division. Here, the authors find the protein HURP to be essential for microtubule formation by stabilizing the ...
Scientists usually have to study cells outside the body, and hope that they’re seeing the normal, natural process. But McNally is taking a different approach. He is eavesdropping on egg development as ...
It's a perilous process. As chromosomes line up in the middle, a mechanized protein scaffold, called the spindle, assembles on either side of that line. On each side, it resembles a squid with its ...
Proteins were transferred onto nitrocellulose membrane (Cytiva-Amersham ... Quantitative analyses of chromosome alignment, spindle length and Kif18A and α-tubulin fluorescence intensity Spindles were ...
European spindle trees, Euonymus europaeus, are low-maintenance, small trees native to much of northern and central Europe. These deciduous trees often grow at the edge of woodlands and forests, ...
Proteins are biopolymers of amino acids (polypeptides), joined by peptide bonds, that are generated by ribosomes. The amino acid sequence, encoded by its gene, determines a protein’s structure ...
Molecular Cellular Pharmacology Graduate Program, University of Wisconsin-Madison, Madison, USA Department of General Surgery, Graduate School of Medicine, Chiba University, Chiba, Japan ...
About VIP943 VIP943, the first ADC from the VersAptx platform, consists of an anti-CD123 antibody, a unique linker cleaved intracellularly by legumain, and a novel kinesin spindle protein ...
VIP943, the first ADC from the VersAptx platform, consists of an anti-CD123 antibody, a unique linker cleaved intracellularly by legumain, and a novel kinesin spindle protein inhibitor (KSPi) payload ...