Spindle fibers form a protein structure that divides the genetic material in a cell. The spindle is necessary to equally divide the chromosomes in a parental cell into two daughter cells during ...

The hybrid microscope can be useful for studying proteins, as they change their 3D orientation in response to their ...

the spindle poles separate as the non-kinetochore microtubules move past each other. These latter movements are currently thought to be catalyzed by motor proteins that connect microtubules with ...

Imaging the molecules in a dividing cell's "spindle," a protein structure that extends from one side of the cell to the other ...

Because the core centromere function of connecting to the spindle is highly conserved across eukaryotes, we expect that centromere components would also be conserved. Contrary to this expectation, ...

Two heads are better than one, as the saying goes, and sometimes two instruments, ingeniously recombined, can accomplish ...

Mitotic spindles are dynamic, self-organizing, intracellular structures that are essential for cell division. Spindles are composed of proteins, cytoskeletal elements and microtubules, which are a key ...

In eukaryotes, segregation of duplicated chromosomes is performed by the mitotic spindle, a cellular machine composed of microtubules and their associated proteins. Spindles are built from ...

Motor motion on cytoskeletal filaments is particularly important for biological length regulation, because numerous proteins targeted to microtubule ends modify their dynamics and can dramatically ...