Briola and co-authors determined the structure of the human CTF18 clamp loader bound to PCNA to high resolution, analyzed the structure, and tested a new mechanism involving a human-specific Ctf18 ...
They form when stretches of cytosine letters on the same DNA strand pair with each other, creating a four-stranded, twisted structure protruding from the double helix. The researchers found that i ...
Deoxyribonucleic acid (DNA) is the information-carrying molecule found in all living organisms. In most animal, plant and fungal cells DNA is stored in the nucleus coiled up in thread-like ...