Cellular immunity is a protective immune process that involves the activation of phagocytes, antigen-sensitized cytotoxic T cells and the release of cytokines and chemokines in response to antigen.

Unfortunately, primary isolated fibroblasts retain limited proliferation potential. To enable robust biochemical experimentation in cardiac fibroblasts we immortalized human cardiac fibroblasts using ...

SV40 large T antigen NLS 是一种多肽，来源于 SV40 大 T 抗原 47-55 的氨基酸序列，能够将蛋白运输到细胞核。 SV40 large T antigen NLS是一种多肽，来源于SV40（Simian Virus 40，猿猴病毒40）大T抗原的特定氨基酸序列，通常位于47-55位。它在生物学和医学研究中具有多种应用和 ...

1Department of Therapeutic Radiology, Yale University School of Medicine, New Haven, Connecticut. 2Department of Genetics, Yale University School of Medicine, New Haven, Connecticut.

T-Mobile is one of the fastest-growing carriers in the United States thanks to aggressive pricing, marketing, and a penchant for doing the unexpected. The Uncarrier has significantly shaken up the ...

Over the years, several variations of HEK 293 cells have been developed to suit specific research needs. One notable variant is the HEK293T cell line, which expresses the SV40 large T antigen. This ...

Chimeric antigen receptor (CAR) T-cell therapy is a way to get immune cells called T cells (a type of white blood cell) to fight cancer by changing them in the lab so they can find and destroy cancer ...

Trey Paul is a CNET senior editor covering broadband. His 20+ years of experience as a writer and editor include time at the broadband marketplace Allconnect, as well as working with clients like ...

How these hexameric helicases interact with their origin dsDNA remains unknown. Here, we report the co-crystal structure of the SV40 Large-T Antigen (LT) hexameric helicase bound to its origin dsDNA.

Here we report studies on the assembly of the human replicative polδ holoenzyme. By utilizing FRET signals from fluorescently labeled P/T DNA and PCNA to monitor protein-DNA interactions, we were able ...