Excitatory synapses are located in confined chemical spaces called the dendritic spines. These are atypical femtoliter-order microdomains where the behavior of even single molecules may have ...

A tiny brain for immense discoveries. The fruit fly, this simple vinegar fly, holds within it the secrets of neural connections. Could understanding its brain pave the way for insights into human ...

The post-synaptic side of the synapse is now recognized as a site ... which focuses on the cell biology of a number of ligand- and voltage-gated ion channels involved in post-synaptic ...

An electrical impulse cannot directly cross the gap so a different mechanism has to be used. Between impulses the transmitter molecules are rapidly removed from the synaptic cleft to prevent ...

Boost Neuroscience is a stealth biotech with a proprietary synapse network platform based on the work of Nobel Laureate Dr. Thomas Südhof, M.D.

"Next, we are studying how to dynamically adapt these CAR T cells at the synapse level to make them more effective." "Tumors are very sophisticated. We need to adapt our tools to the biology of ...

Tau aggregates appear inside synapses from human brain samples with Aβ pathology. The method can be adapted to study other synaptic proteins. As reported in Cell Chemical Biology on January 23, first ...

Last semester, Sarah Trafton (senior, graphic design and illustration) was one of The Penn’s artist features but this semester we are featuring her again for a special reason.

Boost Neuroscience is a “stealth” biotech company that has developed a proprietary synapse network platform ... his work on synaptic transmission and biology. The company, backed by Catalio ...