A defining feature of successful vaccination is the ability to induce long-lived antigen-specific memory cells. T follicular helper (Tfh) cells specialize in providing help to B cells in mounting ...
Ex vivo analysis showed that tumour-infiltrating IL-17+ cells mostly consist of CD4+ T helper 17 (Th17) cells with multifaceted properties. Indeed, owing to IL-17 secretion, CRC-derived Th17 triggered ...
One of the major effects of microbiota is the induction of mucosal T helper 17 (Th17) cells. We therefore reasoned that the efficiacy of Th17-targeted therapies in arthritis may depend on the host ...
G6PI-specific T helper (Th) cell responses were assayed by polychromatic ... Within the pool of G6PI-specific Th cells the frequency of interleukin 17 (IL17), interferon γ or tumour necrosis factor α ...
A study, published in the journal MedComm and led by Dr. Panpan Jiang and collaborators at Tongji Medical College, explores ...
Within the synovium, Tph cells far outnumbered T follicular helper cells, were located in close proximity ... InForm was performed using R V.4.0.016 and the ‘phenoptr’ package.17 Cell co-localisation ...
This valuable study reports on a novel role of PD-1 in early T cell differentiation, showing that PD-1 stimulation impairs Th2 differentiation more effectively than that of Th1, with implications for ...
Recent research published in MedComm highlights how mutations in the Dedicator of Cytokinesis 8 (DOCK8) gene impair the differentiation of helper T cells by affecting their glycolytic metabolism. This ...