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12 小时
2024年蛋白降解: 诺华、辉瑞等均有布局,11款1类创新药在中国首次 ...
据丁香园Insight数据库,截至目前(数据截至2024年11月19日)全球范围内蛋白降解研发管线项目总数已过千,其中超过95款处于临床开发阶段。
1 天
on MSN
TPD: Scammers using fake QR codes at parking lots to steal personal information
Tampa police are warning the community about a scam that targets people looking to use mobile payment methods in city parking ...
FOX 13 Tampa Bay on MSN
15 小时
16-year-old shooting suspect ambushed teenage victim: TPD
A New Hampshire jury on Tuesday found a former leader at a youth detention center guilty of holding down a teen while he was ...
生物通
23 天
一种基于纳米颗粒的靶向蛋白降解通用策略:TPD-NPs
图1靶向蛋白降解胞吞-降解作用新机制 靶向蛋白降解(TPD)是当今生物医药领域的热门研究方向,通过TPD分子将疾病相关蛋白牵引至细胞内的“回收站”进行降解清除,为传统药物难以成药的蛋白质提供了巨大的治疗潜力。但现有的TPD分子为适应不同的疾病靶点 ...
KSNT Topeka on MSN
3 天
TPD investigating 19th homicide
Topeka Police Department is investigating the 19th homicide of 2024.Sunday night, officers responded to a reported shooting ...
1 天
on MSN
Three men promoted during TPD ceremony Tuesday morning
TALLAHASSEE, Fla. (WCTV) - The Tallahassee Police Department held a promotion ceremony Tuesday morning at city hall. Chief ...
Nature
1 年
Transforming the future of targeted protein degradation with the SPiDEM platform
Prazer’s proprietary TPD platform, selective protein degradation enabling moiety (SPiDEM), allows the rational design and rapid optimization of orally available and BBB-penetrating small molecules.
KSNT Topeka on MSN
5 天
TPD investigating shooting in North Topeka
The Topeka Police Department (TPD) is investigating a shooting that happened Friday evening in North Topeka. Just after 5:30 ...
Toledo WTVG on MSN
1 天
TPD: Man punched woman, forced her into vehicle
TOLEDO, Ohio (WTVG) - A man faces multiple felony charges for allegedly assaulting a woman before forcing her into a vehicle ...
生物通
12 天
Cell | 复旦大学鲁伯埙和丁澦受邀撰写SnapShot,聚焦靶向降解技术研究
复旦大学生命科学学院鲁伯埙和丁澦受《 Cell 》杂志主编 Luis Gomes 邀请,撰写了题为 Targeted Degradation Technologies 的 SnapShot ,系统介绍了靶向降解技术的发展现状、主要类别、作用机制及其在药物发现中的应用潜力,该文于 2024 年 11 月 14 日在《 Cell 》上正式发表 ...
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