据丁香园Insight数据库,截至目前(数据截至2024年11月19日)全球范围内蛋白降解研发管线项目总数已过千,其中超过95款处于临床开发阶段。
Tampa police are warning the community about a scam that targets people looking to use mobile payment methods in city parking ...
A New Hampshire jury on Tuesday found a former leader at a youth detention center guilty of holding down a teen while he was ...
图1靶向蛋白降解胞吞-降解作用新机制 靶向蛋白降解(TPD)是当今生物医药领域的热门研究方向,通过TPD分子将疾病相关蛋白牵引至细胞内的“回收站”进行降解清除,为传统药物难以成药的蛋白质提供了巨大的治疗潜力。但现有的TPD分子为适应不同的疾病靶点 ...
The onset or progression of many refractory diseases, including neurodegenerative disorders and cancers, is caused by the accumulation of proteins. Targeted protein degradation (TPD) has emerged ...
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TPD investigating 19th homicide
Topeka Police Department is investigating the 19th homicide of 2024.Sunday night, officers responded to a reported shooting ...
TALLAHASSEE, Fla. (WCTV) - The Tallahassee Police Department held a promotion ceremony Tuesday morning at city hall. Chief ...
The Topeka Police Department (TPD) is investigating a shooting that happened Friday evening in North Topeka. Just after 5:30 ...
复旦大学生命科学学院鲁伯埙和丁澦受《 Cell 》杂志主编 Luis Gomes 邀请,撰写了题为 Targeted Degradation Technologies 的 SnapShot ,系统介绍了靶向降解技术的发展现状、主要类别、作用机制及其在药物发现中的应用潜力,该文于 2024 年 11 月 14 日在《 Cell 》上正式发表 ...