A photothermal, nanoparticle-based deep brain stimulation system restored motor skills in mice with Parkinson’s-like disease ...

Investigators at the Jacobs School of Medicine and Biomedical Sciences have uncovered how heat causes a critical receptor protein within cells to unfold and relay pain, which could open up new ...

A new study reveals that scratching is not just an annoying reflex — it plays a dual role in immune activation and pathogen ...

It's all about a chemical compound in peppers called capsaicin. Capsaicin binds to pain receptors on our nerves called TRPV1. Normally, it reacts to heat by sending warning signals to the brain.

This wireless DBS nanosystem primarily has three advantages: It leverages the endogenously expressed TRPV1 receptors in dopaminergic neurons of the substantia nigra, eliminating the need for ...

Bsense Bio Therapeutics Ltd. has disclosed new potassium voltage-gated channel subfamily KQT member 2/3 (KCNQ2/3) activators and transient receptor potential cation channel subfamily V member 1 (TRPV1 ...

Some of the central molecular mechanisms that lead to hyperalgesia and allodynia after peripheral tissue injury involve the spinal dorsal horn transient receptor potential vanilloid 1 (TRPV1).