For the first time, researchers have used lab-grown organoids created from tumors of individuals with glioblastoma (GBM) to ...

The regulator HIF1α functions in a cancer-microenvironment that lacks oxygen, and it may be involved in resistance to immune ...

Beta-hydroxybutyrate (BHB), a ketogenic diet metabolite, enhances CAR T cell activation, offering a cost-effective boost for ...

The novel link between nutrition and cell identity offers a new explanation for exhausted T cell identity and in turn, offers ...

Immune checkpoint blockades, or ICBs, have revolutionized treatment for various advanced cancers. However, their ...

Research shows that GBM organoids are a powerful, accurate tool for understanding what happens when treating a brain tumor ...

The relationship the immune system and stromal cells in pancreatic cancer can have a significant impact on patients' survival ...

Demehri, MD, Ph.D., of the Department of Dermatology and Center for Cancer Immunology at Massachusetts General Hospital, is ...

Scientists have discovered that our specialized immune cells, called T cells, are what they eat -- their switch from functional to 'exhausted' depends on the switch from metabolizing acetate to ...

The selection of this first target is a key step for the partnership between Medigene and WuXi Biologics, which aims to advance multiple TCR-TCEs over the next three years. The collaboration seeks to ...

A new study suggests certain lipids, particularly omega-6 fatty acids, which are commonly found in seed oils used to make ...

IFN-γ capture assay enriches tumor-reactive T cells from immunized mice. Figure 3: IFN-γ capture assay detects and enriches tumor-specific T cells from human RCC. In conclusion, the method ...