Chemoradiation is considered a reasonable treatment option for patients with locally advanced, unresectable pancreatic cancer. The chemotherapy agents 5-fluorouracil, gemcitabine, capecitabine and ...

This new review article highlights the crucial role of GATA6, a transcription factor, in pancreatic ductal adenocarcinoma ...

Classification of Locally Advanced Pancreatic Adenocarcinoma Into Type A and B and Comparison ... For patients who are deemed unresectable, consideration should be given to definitive chemoradiation ...

Pancreatic ductal adenocarcinoma (PDAC ... Cullen and colleagues conducted a prior trial for patients with unresectable pancreatic cancer, and three of the 14 patients survived beyond 9 years.

Novocure (NVCR) plans to file for regulatory approval of TTFields in unresectable, locally advanced pancreatic adenocarcinoma based on PANOVA-3. The company is also exploring the use of TTFields ...

The phase 1 trial results, published Feb. 19 in Nature, evaluated the personalized mRNA neoantigen vaccine autogene cevumeran in combination with surgery, immunotherapy drug atezolizumab and ...

Hence, they are classified as locally-advanced, surgically unresectable (stage III ... of patients with histologically-proven pancreatic ductal adenocarcinoma at this point in time is 19.6 ...

UTRECHT, The Netherlands and CAMBRIDGE, Mass., Feb. 05, 2025 (GLOBE NEWSWIRE) -- Merus N.V. (Nasdaq: MRUS) (Merus, the Company, we, or our), a ...

evaluated TTFields therapy in combination with gemcitabine and nab-paclitaxel as a first-line treatment for unresectable, locally advanced pancreatic adenocarcinoma. The trial met its primary ...

Zenocutuzumab helps fill an important need for patients with advanced pancreatic cancer and NSCLC with NRG1 gene fusions, said Alison Schram M.D., ...

High disease control rate and strong interim safety results observed in pancreatic ... for recurrent unresectable or metastatic head and neck squamous cell carcinoma (HNSCC), a systemic objective ...