Autoimmune responses to tissue-restricted self-antigens both humoral (antibody mediated) and cellular (predominantly of the IL-17 type) are pathogenic for chronic rejection. Alloimmune responses ...

A NOVEL autoimmune meningoencephalomyelitis associated with autoantibodies targeting the astrocytic intermediate filament protein vimentin has been identified in a recent case series. This discovery ...

Background: GDF15 is a potential biomarker for patients with esophageal cancer (EC). However, the mechanistic role of GDF15 in the invasion and metastasis of EC remains poorly understood. Methods: We ...

Researchers from the University of Pittsburgh and NIH developed a broadly neutralizing antibody that protects monkeys from severe H5N1 avian flu by targeting a stable region of the virus, reducing the ...

They are a type of medical treatment. Scientists make monoclonal antibodies, or mAbs, in a lab. They work like the natural antibodies your body makes to fight illness. They go out into your body ...

You can get in touch with Ian by emailing [email protected]. Languages: English. Antibody-based immune therapy could become a key weapon in the fight against bird flu after trials in monkeys ...

The antibody targets a stable part of the bird flu virus, ensuring that the immune protection can resist new variants and offer long-term protection against the globally spreading airborne infection.

Treatment of lung ACE2/A549 carcinoma cells with purified vimentin or coculture of ACE2/A549 cells with HEK-293 cells expressing vimentin increased ACE2-dependent viral entry. CR3022 antibody blocked ...

Therefore, this monoclonal antibody can be used as a marker monoclonal antibody for NS1 protein in JEV and provide material for subsequent WB detection experiments. Figure 3. Identification of ...

For decades, lab-made antibodies have been used to support patients fighting specific diseases. These treatments have become a cornerstone of cancer therapy and were among the first medical ...