Vimentin is a type III intermediate filament (IF) protein normally expressed in cells that develop into connective tissue, blood vessels, and lymphatic tissue (mesenchymal cells). Despite being widely ...

Circulating breast cancer cell expressing vimentin. Arrow indicates a circulating breast cancer tumor cell: positive for vimentin expression (FITC, green); negative for cytokeratin expression (red).

Changes to the intermediate filament (IF) protein, vimentin, were found to promote tumor growth by increasing cancer stemness in an oestrogen independent manner. Targeting vimentin and/or the long ...