The virus particle comes apart, releasing the viral genome. The viral RNA (vRNA) is translated into a single polypeptide that is cut into ten proteins, and the viral genome is replicated.

The path forward for a T-cell-based vaccine against HIV remains unclear, with problems such as vaccine immunogenicity, vector-specific ... and the two copies of viral RNA that are complexed ...

As the particles are often pseudotyped with the envelope of the vesicular stomatitis virus (VSV), the vector can serve to introduce genes into a broad range ... These features, in conjunction with ...

Ottawa, Feb. 19, 2025 (GLOBE NEWSWIRE) -- The global viral vector and plasmid DNA manufacturing market size was valued at USD 7.19 billion in 2024 and is expected to be worth around USD 46.02 ...

Even before COVID-19 swept across the globe this year, coronaviruses were on scientists’ radar as pathogens that could one day ignite a pandemic. They’d threatened to before—in 2002–03, the SARS virus ...

MicroRNAs function by binding to a matching piece of messenger RNA that encodes a protein and decreasing the production of that protein. Viral RNA with a base sequence complementary to that of ...

Several antiviral and anticancer drugs target the incorporation of adenine into DNA or RNA. For example, some nucleoside analog drugs, such as vidarabine and fludarabine, mimic adenine and interfere ...