Research uncovers tumor cell cooperation via CNDP2, suggesting new therapeutic strategies that disrupt nutrient sharing to ...

The Bachovchin lab uses chemical and cell biology approaches to study important questions in innate immunity. We are particularly interested in characterizing the molecular mechanisms controlling the ...

p53 is a transcription factor that regulates the expression of genes involved in tumor suppression. p53 mutations mediate tumorigenesis and occur in approximately 50% of human cancers. p53 regulates ...

Transmissible gastroenteritis virus (TGEV) is a porcine coronavirus that threatens animal health and remains elusive despite years of research efforts. The systematical analysis of all available ...

S-Palmitoylation is the only reversible post-translational lipid modification. Knowledge about the DHHC palmitoyltransferase family is still limited. Here we show that human ZDHHC6, which modifies key ...