Their pathogenesis is a consequence of hyperproliferation, hypersecretion and microRNA alterations in cholangiocytes. Here we evaluate the role of matrix metalloproteases (MMPs) in the hepatic ...

Here, we review hiPSC technology of cell reprogramming and differentiation, and discuss the potential application of hiPSC-derived liver cells, such as hepatocytes and cholangiocytes, in refractory ...

Circulation of the same molecules is represented in red arrows for hepatic cholestasis. In healthy liver, BA are synthesized from cholesterol in hepatocytes and secreted via cholangiocytes into the ...

9 Affiliated Cancer Hospital and Institute of Guangzhou Medical University, Guangzhou, China Objective Metastasis is the major cause of cancer death. However, what types of heterogenous cancer cells ...

This study provides important insights into the regulation of type-I interferon signaling and anti-tumor immunity, demonstrating that ORMDL3 promotes RIG-I degradation to suppress immune responses.