Background: This study aimed to investigate whether early unfractionated heparin (UFH) administration provides a survival advantage for patients with sepsis-induced coagulopathy (SIC). Methods: ...

Patients with acute promyelocytic leukemia (APL) often present with potentially life-threatening hemorrhagic diathesis. The underlying pathomechanisms of APL-associated coagulopathy are complex.

These data illustrate the importance of rapid and effective coagulopathy reversal. This article will review the current anticoagulation options for vitamin K antagonists (VKAs) or novel oral ...