A scientist at The University of Texas Health Science Center at San Antonio (UT Health San Antonio) has discovered that halting a pathway triggered in the brain during stressful situations could ...

Migraines are more than just bad headaches; they stem from a genetic neurological disease that causes suffering for one in ...

Preventive therapies targeting calcitonin gene-related peptide (CGRP)—ie, monoclonal anti-CGRP or anti-CGRP receptor antibodies, which are injected subcutaneously or intravenously, and gepants, which ...

Aeovian Pharmaceuticals Inc. has prepared tricyclic fused imidazole compounds acting as ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 (CD38) inhibitors reported to be useful for the treatment of ...

Vasoactive Intestinal Peptide (VIP) is an intriguing neuropeptide with a wide range of potential biological impacts, primarily hypothesized in tissues, cells, and internal systems. Since its discovery ...

The ability to characterize the pulmonary circulation more fully paved the way for many advances. In the 1950s, Dr David ...

The Global Pulmonary Arterial Hypertension (PAH) Treatment Market is set for steady growth, with an estimated market size of ...

Roy and Diana Vagelos Laboratories, Department of Chemistry, University of Pennsylvania, 231 South 34th Street, Philadelphia, Pennsylvania 19104-6323, United States ...

Expert Rev Clin Pharmacol. 2012;5(3):319-336. Finally, a recent study suggested that although prasugrel significantly reduces thrombotic events in patients with ACS undergoing PCI because of its ...

Cyclic AMP (cAMP) is generated by nine membrane-bound adenylyl cyclases (AC1–AC9) and one soluble isoform (sAC). Many drugs target cAMP signalling pathways through their respective G-protein ...

This is an important study to reveal local circuit mechanisms in the POA that control body temperature and also highlight how neurotransmitter GABA and neuropeptide NTS from the same neurons ...

This paper will be of interest to scientists in the field of T cell biology and immunometabolism. The data analysis is rigorous and the experiments performed are appropriate. The findings of the ...