Healio4d
Phase 1 trial of potential treatment for IPF moves forward ‘without any safety concerns’
No safety concerns emerged in part one of the phase 1 trial assessing CS014, a histone deacetylase inhibitor that has ...
BioWorld9d
Potential first-in-class FEM1B-recruiting histone deacetylase degraders divulged
Targeted protein degradation (TPD) is an alternative to conventional protein inhibition that is gaining attention due to advantages such as ensuring complete elimination of the target protein, reduced ...
idw6d
Ablation of HDAC8 accelerates the regeneration of neurons and the recovery of the sensory function
N. Hertzog et al., Hypoxia-induced conversion of sensory Schwann cells into repair cells is regulated by HDAC8, Nature Communications, 9 January 2025, DOI: 10.1038/s41467-025-55835-9 ...