Hyperglycemia increases flux through the hexosamine pathway. From Brownlee M: Biochemistry and molecular cell biology of diabetic complications. Nature 414:813-820, 2001.
Further extension of these studies necessitated the synthesis of a series of hexose and hexosamine sulphate esters. Methods for the sulphation of carbohydrates have been re-examined and procedures ...
One potential metabolic pathway of increasing importance is the hexosamine biosynthesis pathway (HBP). The HBP utilizes glycolytic intermediates to generate the metabolite UDP–GlcNAc. This and other ...