The mechanism by which patients with portal hypertension develop portal hypertensive gastropathy has yet to be fully clarified. Its pathogenesis is known to be multifactorial, involving elevations ...

Several epidemiologic studies associate bone-resorbing chronic inflammatory conditions with increased risk of atherosclerotic heart disease. These include post-menopausal osteoporosis, spinal cord ...

Bone remodeling involves a balance between bone resorption and formation. The mechanisms underlying bone remodeling are not well understood. DEF6 is recently identified as a novel loci associated with ...