Lipidomics revealed upregulation of lysophosphatidylcholine 16:0 (LPC16:0), a product of lipid oxidisation, in stressed mice. Intramuscular LPC16:0 injection triggered nociceptive responses and a ...

Pain and stress are both phenomena that challenge an individual’s homeostasis and have significant overlap in conceptual and physiological processes. Allostasis is the ability to adapt to pain and ...

Decades of research advances have established a central role for endogenous opioid systems in regulating reward processing, mood, motivation, learning and memory, gastrointestinal function, and pain ...

A new Swedish study has, for the first time, shown a link between rheumatoid arthritis (RA) and cognitive decline in dementia patients. The study, published in the journal Neurology, emphasizes ...

4 Center of Physical Education and Sport, State University of Londrina (UEL), Londrina, Parana, Brazil Background The temporal and insular cortex (TC, IC) have been associated with autonomic nervous ...

Background: Non-steroidal anti-inflammatory drugs (NSAIDs) are recommended for multimodal postoperative pain management. We evaluated opioid-sparing effects and rehabilitative results after ...

1 Institute of Pathology, University Hospital, Friedrich Schiller University, Jena, Germany 2 Institute of Physiology I, University Hospital, Friedrich Schiller University, Jena, Germany Background ...