Cancer epigenetics is the study of somatically heritable changes to molecular processes that influence the flow of information between the DNA of cancer cells and their gene expression patterns ...

The matched pairs of cancerous and corresponding noncancerous tissues from the same patient collected during surgery were immediately stored at −80°C and then in liquid nitrogen. Genomic DNA and mRNA ...

Recent advances in global methylation profiling coupled with the use of mouse models suggest that aberrant promoter hypomethylation is also a frequent event in hematologic malignancies, particularly ...

Genes in a cell can be switched on or off at different times depending on the cell’s requirements. Small chemical groups can be attached to the gene’s DNA, which dictates whether it is activated or ...