Adeno-associated virus 2 (AAV)-based vectors have gained attention as a potentially useful alternative to the more commonly used retroviral and adenoviral vectors for human gene therapy.

This study convincingly shows that aquaporins play a key role in blood vessel formation during zebrafish development. In particular, the paper implicates hydrostatic pressure and water flow as ...

Background: Transcription factor 4 (TCF4) is found to be associated with schizophrenia. TCF4 mutations also cause Pitt-Hopkins Syndrome, a neurodevelopmental disorder associated with severe mental ...