Mayo Clinic's Precision Mouse Engineering Core in Minnesota makes embryonic stem (ES) cell-based gene-targeted mice available to researchers.

欢迎大家探索2024年度STAR Protocols编辑精选论文合集！可重复性是科学研究进步的核心。准确报告研究方法有助于对研究发现进行严格测试，并增加结果的可信度。STAR Protocols编辑们精选了各自专业领域2024年发表的最具代表性的论文 ...

A new research paper was published in Oncotarget, Volume 16, on February 18, 2025, titled “Robust p53 phenotypes and ...

Phenotypic diversity exists even within isogenic populations of cells. Such nongenetic individuality may have wide implications for our understanding of many biological processes. The field of ...

Shen et al. report a method for multiplexing isogenic iPSCs for single-cell RNA-seq. With it, they created an atlas of in vitro differentiation and identified TMEM88 as a regulator of ...

This concentration allows susceptible strains to continue growing at a reduced growth rate. Figure 2. Growth of the susceptible and the isogenic resistant bacteria in the sub-MIC selective window and ...

Inhibition of nonsense-mediated decay turns immunologically cold tumors hot by increasing the amount of mutant RNA leading to an increase in T-cell-targetable neoantigens on the cell surface.

A biorepository is a place, similar to a library or bank, where biological samples are stored for use in research. Since 2006, the Cystic Fibrosis Foundation has collected and stored samples from a ...