The study reported here utilized a relatively large collection of sibship histories of leukemic children for this purpose. Twelve medical groups participated in the National Cooperative Leukemia ...

"We found that using leukemic cell lines can lead to misleading results in drug discovery," said Wilhelm. "These cell lines do not grow in the same way as cells taken from patients." The efficacy ...

Colony-forming cell assays indicated that the leukemic bone marrow (BM) plasma inhibited erythroid colony formation, whereas they had no inhibitory effect on other types of colonies. Cytokine ...

In the following study, we present the dynamics of the VAFs of somatic variants across different disease stages and demonstrate correlations between associated biological pathways and leukemic ...

The Kharas lab is working to identify critical pathways in both normal and leukemic hematopoietic cells. MSK investigators have used a lab tool originally developed to study fly nerve cells to uncover ...

Introduction: A unique feature of chronic lymphocytic leukemia (CLL) is the increased number of circulating T cells preventing malignant B cells from undergoing apoptosis. Dysregulated expression of ...